Humans have used cannabis for thousands of years, since Neolithic peoples sought out its medicinal benefits. But for the past century, its use has been largely criminalized. Stigma around cannabis has made it difficult for people of all ages to get straightforward answers about how to minimize health risks related to cannabis consumption or to understand how the plant has shaped and continues to shape society today. In Weed: Cannabis Culture in the Americas, culture writer Caitlin Donohue crafts a comprehensive and thought-provoking review of cannabis in the Western Hemisphere. Donohue’s investigation spans from Vancouver, Canada, to Buenos Aires, Argentina, interviewing medical researchers, educators, activists, artists, business leaders, and other experts to explore the long relationship between cannabis and the human race, its almost universal prohibition in the twentieth century, and modern efforts to legalize the much-maligned plant in all its forms.